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acne medication
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sebaceous glands
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there have been many cases
Isotretinoin Acne Medication Is Dangerous To Your Health – There Are Better Solutions
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Isotretinoin Acne Medication is Dangerous to Your Health – There Are Better Solutions

With recent news of the British mother-to-be having a miscarriage of her 20 week fetus, due to the toxic effects of the powerful isotretinoin acne medication, I’d like to put a spotlight on this dangerous drug. The generic brand of isotretinoin that she was given was called Roaccutane. It caused severe heart and nervous system abnormalities which led to the death of her unborn baby.

Drug Development and Removal from Market

Isotretinoin was first marketed in 1982 under the brand name Accutane by the Swiss pharmaceutical company Hoffmann-La Roche, as a medication to control cystic acne. Studies suggested the drug reduces sebum production by causing cell destruction within sebaceous glands, inside hair follicles, and also has an antimicrobial effect on Propionibacterium acnes deep within the tissues of the skin. Isotretinoin’s effect on sebum production has sometimes been found to be only temporary.

Isotretinoin was also approved as a chemotherapy treatment against some cancers, including brain and pancreatic. Chemotherapy drugs are toxic. Because oral isotretinoin is ingested, its effects are systemic and nonselective, meaning that not only does it poison and kill acne bacteria and cells within the sebaceous glands within the skin, but it poisons and kills other cells of the body as well. Developing fetuses are especially susceptible to its effects.

In 2009, Roche Pharmaceutical pulled the drug off the market in 12 countries including the U.S., due to a wave of lawsuits in which the pharmaceutical lost all of them and was forced to pay millions in fines. One such lawsuit was a high-profile case of the rising young movie star, James Marshall, in which Accutane had caused ‘Inflammatory bowel disease’. In other words, it damaged his colon so horribly that he had to have his colon removed and fitted with a colostomy bag. This essentially ended his movie career. There have been many cases of severe adverse effects by this dangerous compound.

Poisoned by My Isotretinoin Acne Medicine

Isotretinoin's molecule closely resembles retinoic acid, which is a natural vitamin A. Similar to vitamin-A, this fat soluble compound is stored in the liver where it will build up in quantity. In very small doses, vitamin-A can actually have some benefits, like boosting the immune system and aiding vision, however, large doses of vitamin-A has many severe toxic effects on the body.

When dermatologists treat patients for severe cystic acne with isotretinoin, it is prescribed in high-dose treatments. The toxic effects are very similar to high doses of vitamin-A. The most common side effects are bone, musculature, and connective tissue pain, eye irritation and dryness, vision blurriness, and reduced night vision, anemia and increased cholesterol, dry irritated skin and rash, to name a few.

Isotretinoin's less common, though far more serious side-effects include inflammatory bowel disease, crohn's disease, ulcerative colitis, and gastrointestinal bleeding, depression and suicidal tendencies, just to name a few.

Today, although Accutane is now unavailable, oral isotretinoin is still marketed under several manufacturers, under the generic brand names: Roaccutane, Accure, Aknenormin, Amnesteem, Ciscutan, Claravis, and many more.

Pregnancy Risks

Isotretinoin causes developmental malformations in developing fetuses, and if taken by women during pregnancy, will practically guarantee birth defects. The common birth defects this drug causes are mental retardation, facial malformations, severe heart defects, brain and nervous system abnormalities, hearing and visual impairment, missing or malformed earlobes, just to name a few. Deaths and severe birth defects to fetuses have been widely documented with its usage during pregnancy.

Restrictions to Prescribing Isotretinoin

Because of the potential risks to fetuses, in the United Kingdom, isotretinoin may only be prescribed under the supervision of a dermatologist. In the United States, dermatologists must register their patients to a national online list, a program called iPledge, before prescribing it to patients. Pharmacists are then required to check the website before dispensing the drug. Strict adherences to pregnancy testing and dual contraception methods by women are also required.

Better Alternatives to Treat Acne

Isotretinoin for acne is not worth serious risks it poses to your health. I personally wouldn’t recommend using this poison for whatever reason.

Although severe acne can cause mental anguish, it’s not a life threatening condition. Fortunately, there are many highly-effective ways to naturally treat acne, and some promising research that’s recently been in the news:

  • Topically applied, combination dose of adapalene and benzoyl peroxide.
  • Discovery of multiple strains of p.acnes bacterium, only some of which cause acne.
  • Using the natural anti-bacterial properties of safe, natural Tea Tree Oil to attack acne causing bacteria, topically
  • Beta hydroxy acids (salicylic acid) which is oil soluble and able to penetrate into the hair follicles that contain sebum oil to exfoliate (shed) the dead skin cells within.
  • Superior effectiveness of encapsulated benzoyl peroxide in killing p.acnes acne over conventional benzoyl peroxide, or prescription antibiotics
  • New Evidence that the avoidance of inflammation-causing foods, and improving immunity is having a profound positive effect against acne.
Quick Tips for a Clear Complexion

Here are some easy, non-toxic ways to help reduce acne

  • Drink plenty of water – Reduce or avoid sugary drinks and chemical sweeteners.
  • Greatly reduce your consumption of sugars, processed flours and carbohydrates, which is well documented in causing inflammation in the organs and joints.
  • Eat organic carrots, dark-green leafy vegetables, and other brightly-colored organic vegetables.
  • Wash your face twice daily with a good over counter acne treatment.
  • Avoid hydrogenated oils (trans-fats) and increase omega-3 fatty acids in your diet.
  • Avoid food with genetically modified ingredients.

Acne treatments don’t always affect people in same way, so you may need to try different things, or maybe a combination of things, but keep in mind that diet plays a big part in the body’s ability to maintain a healthy immune system and maintain a healthy skin complexion.

Street Talk

Good advice. Like you, I believe there are plenty of more natural ways to be rid of acne.

  about 9 years ago

Thanks for the comment Chip. I agree with you completely. There are effective ways to deal with acne, without the toxicity.

  about 9 years ago
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