Genetics And Parkinson’s Disease
Join 1000's of Authors at StreetArticles Today!

Parkinson’s Disease:

A chronic progressive neurological disease chiefly of later life that is linked to decreased dopamine production in the substantia nigra. There are many symptoms which affect the patient very seriously and creates much problem in daily life.

Genetics:

Genetics is a study of heredity, or how the characteristics of genetics are transmitted from one generation to the next. All living things contain genetic material that makes up DNA molecule.

Contribution of genetics in Parkinson’s disease:

Approximately 15% of people with Parkinson’s disease have a family history of this disorder. Families cases of Parkinson’s disease can be caused by mutations in the LRRK2, PARK2, PINK1 or gene, or by alterations in genes that have not been identified.

Genetics In Parkinson’s Disease:

15% of Parkinson’s cases have been linked to a genetic cause. Most cases of Parkinson’s are called idiopathic or sporadic, meaning the case is known and researchers believe onset is due to a combination of genetic and environmental factors. It is not fully understood how genetic changes cause Parkinson disease or influence the risk of developing the disorder. Many Parkinson disease symptoms occur when nerve cells (neurons) in the substantia nigra die or become impaired. Normally, these cells produce a chemical messenger called dopamine, which transmits signals within the brain to produce smooth physical movements. When these dopamine-producing neurons are damaged or die, communication between the brain and muscles weakens. Eventually, the brain becomes unable to control muscle movement. In most cases of Parkinson disease, protein deposits called Lewy bodies appear in dead or dying dopamine-producing neurons. (When Lewy bodies are not present, the condition is sometimes referred to as parkinsonism.) It is unclear whether Lewy bodies play a role in killing nerve cells or if they are part of the cells' response to the disease.

How Do People Inherit Parkinson’s Disease:

Most cases of Parkinson’s occur with no apparent family history of the disorder. Among familial cases of Parkinson disease, the inheritance pattern differs depending on the gene that is altered. If the LLK2 or SNCA gene is involved, the disorder is inherited in an autosomal dominant pattern. When genetic alterations modify the risk of developing Parkinson disease, the inheritance pattern is usually unknown.

Using Genetics Diagnose And How To Treat Parkinson’s Disease:

By discovering genes linked to Parkinson’s, scientists can develop tests to find out who is at risk of developing Parkinson’s and can begin to diagnose it early, even before symptoms are obvious. Leading to strategies which may lessen the amount of synuclein in the cells of people with Parkinson’s. It is hoped that someday in the future, this method may help lessen, or hopefully even reverse Parkinson’s disease. Parkinson’s does not have complete cure, but different medications, therapies and strategies could help in reducing the symptoms. This insight into the basic biological cause of Parkinson’s disease has led to ideas for treatments.

For More Info Visit Now : Treatment For Parkinson‎


Street Talk

No comments present
You May Also Like
Fighting the Stigma Surrounding Big Pharma
When people think ‘big pharma’, they think ‘big money’ – and they’re not wrong. Egypt’s central bank just allocated $120 million to the importation of medical supplies for citizens due to recent shortages. Capital Crop Merchant banking recently invested $8.4 million to an Albanian pharmaceutical manufacturing plant. An additional £20…
By: Jeff Nevil in  Health and Fitness  >  Healthcare Systems   May 28, 2016  
0
  Likes: 0

Some Useful Tipes For Buying Valuable Salt Spray Chamber
When there is a requirement check or valuate a selected product and/or coating for the resistance to corrosion a test technique known as salt spray testing is usually used. It is a well-liked and price effective corrosion testing method. The testing takes place in an self-enclosed temperature controlled chamber wherever…
By: Oracleequipments in  Health and Fitness  >  Healthcare Systems   May 17, 2016  
0
  Likes: 0

Get Cheapest Cost Hip Replacement Surgery at Fortis Hospital Mumbai In India With Endless Benefits
Pain in hips due to a number of reasons are common ailments, which one can often hear from all the age group of people particularly from the older ones. Though one can find a number of non-surgical options to resolve these issues but when these treatment fail to work then…
By: Lena rivera in  Health and Fitness  >  Healthcare Systems   May 17, 2016  
0
  Likes: 1

New Trends In Fertility Treatment Abroad – Praga Medica
According to research, one out of eight couples in America has fertility problems. Sadly, most couples tend to wait it out, which is not doing them any favors. The longer the wait, the lower the chances of getting pregnant. Thanks to research in fertility treatments, success rates have greatly improved.…
By: David Fiala in  Health and Fitness  >  Healthcare Systems   Apr 27, 2016  
0
  Likes: 0

What Do You Know About Female Hair Transplant?
When it comes to hair transplants, men's transplants are more common than the women's are. This is perhaps because hair loss is more common in men than in women. Hair loss in a woman in many of our societies is an unattractive feature as opposed to baldness in a man.…
By: Sundas Qasim in  Health and Fitness  >  Healthcare Systems   Apr 26, 2016  
0
  Likes: 0

What Do You Know About Female Hair Transplant?
When it comes to hair transplants, men's transplants are more common than the women's are. This is perhaps because hair loss is more common in men than in women. Hair loss in a woman in many of our societies is an unattractive feature as opposed to baldness in a man.…
By: Sundas Qasim in  Health and Fitness  >  Healthcare Systems   Apr 26, 2016  
0
  Likes: 0

6 Steps Of Revalidation For Locum Doctors
Medical appraisal is a basis of GMC revalidation. It is conducted annually in which a meeting takes place between the appraised doctor and the appraiser who is usually a colleague trained as an appraiser. The medical appraisal process has three stages. Inputs for appraisal The confidential discussion of appraisal Outputs…
By: molanparker in  Health and Fitness  >  Healthcare Systems   Apr 15, 2016  
0
  Likes: 0

How Long Do Freeze Dried Vegetables Last?
Freeze drying is one of the processes of preservation where the food is kept at low temperature till it solidifies and then subjected to high vacuum that removes ice by sublimation. This is done to prevent the food from spoiling and damage, giving it a longer lifespan, around 25 to…
By: motherearthproduct in  Health and Fitness  >  Healthcare Systems   Apr 12, 2016  
0
  Likes: 0

The Importance Of Healthcare Logistics
Changing political conditions, as well as an increasing pressure of rising costs in the healthcare sector, has made a steady alignment necessary in this field. Economical and efficient services in healthcare logistics, which can adjust the things flexibly, can provide essential advancement in the fields of medicine, research and care…
By: Jeff Nevil in  Health and Fitness  >  Healthcare Systems   Apr 11, 2016  
0
  Likes: 0

The Clinical Trial Of the Future
As a means to possibly save thousands of lives, clinical trials are important. However, the means and resources with which these trials are conducted is stagnating in comparison to other equally essential areas of the healthcare industry. Clinical trials are meant to establish the effectiveness of pharmaceutical products, enlisting specific…
By: Jeff Nevil in  Health and Fitness  >  Healthcare Systems   Apr 06, 2016  
0
  Likes: 0

Top 5 Health And Fitness Apps for Androi
Android brings a drastic change to life. Now, you can access a number of incredible apps right after a successful download. One of the greatest options is to downloadhealth and fitness apps. Nowadays, people are more concern about health and fitness issues. They want to learn more about health and…
By: annylisa in  Health and Fitness  >  Healthcare Systems   Mar 30, 2016  
0
  Likes: 0

How to Save Money on Expensive Haircuts
Everybody wants to take care of their hair. It is just that most people don’t think it is something they can afford. Hair treatments by most people’s account are considered a luxury and not a necessity when in fact it is. When you don’t have your hair cut regularly, it…
By: AndersonHamilton09 in  Health and Fitness  >  Healthcare Systems   Mar 29, 2016  
0
  Likes: 0

Benefits Of IVF Fertility Treatment Abroad In Czech Republic
According to statistics, one in eight couples may have trouble getting pregnant. It is no wonder the demand for IVF fertility treatment abroad has been on the rise. But the trouble with IVF treatment—especially in countries like the US and the UK—is that it’s expensive and inaccessible. And even if…
By: David Fiala in  Health and Fitness  >  Healthcare Systems   Mar 24, 2016  
0
  Likes: 1

Do You Called for A Urology Expert In India?
A urology medical professional is one that determines along with treats people that are struggling with illness that affect the urinary and also reproductive organs. It does not matter if you have really been spotted with a pee infection or urological cancer cells; you still have to consult a friendly…
By: Manidipta Roychowdhury in  Health and Fitness  >  Healthcare Systems   Mar 16, 2016  
0
  Likes: 0

What is FUE Transplant & their Advantages
What is FUE hair transplant Follicular Unit Extraction better known by its acronym “FUE”, is one of the fastest growing cosmetic treatments for those who are looking to regain a thick layer of hair on their head. The method of treatment involves obtaining follicular units, which are the naturally occurring…
By: Sundas Qasim in  Health and Fitness  >  Healthcare Systems   Mar 15, 2016  
0
  Likes: 0

Article Views: 562    Report this Article