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chemical reactions
For The Obese, Slow And Steady May Win The Race
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For the Obese, Slow And Steady May Win the Race

Dieters usually want to lose weight as quickly as possible, but for the seriously obese, that might not be the best option. According to a new study by the University of Illinois, obese people may trigger an adverse chemical reaction in the brain that may derail any type of weight loss efforts. That study, which is being published in the latest edition of Obesity Journal was led by Gregory G. Freund, a Professors in the University of Illinois College of Medicine and a member of the school’s Division of Nutritional Sciences.

According to the study’s results, obese people should never kick off any type of weight loss plans or diet with a fast or cleanse. Either may set off a number of serious chemical reactions that may affect the immune system and may work against the efforts to lose weight. People who are obese should plan to take a longer time to lose the weight, taking smaller steps in their weight loss journey so that they can have not only positive results as well as long term results as well.

The study focused on two groups of mice. For twelve weeks, the mice were fed either a low fat diet which got only ten percent of its calories from fat or a high fat diet which got over half of its overall calories from fat. The high fat diet fed mice ended up becoming seriously obese during the study. At the end of the twelve weeks, the two groups of mice were put on a twenty four hour fasting cleanse. The mice from the low fat diet group lose nearly twenty percent of their body weight during the fast while the high fat mice group only lost five percent.

Freund stated that there is an immune system reaction and complication during fasting or a cleanse in an obese person that is not fully understood and to this point has not even been studied. Fasting may enact an anti-inflammatory reaction in the body of a leaner person but have no such reaction on the obese person. Other brain based chemicals that are prevalent in the leaner person is also missing in the obese.

Obese animals seem to resist the regulation of certain chemicals and hormones related to weight control that leaner animals have. While this was not the only reason that they became obese, it certainly did play a role. It also showed that just changing the diet and other habits may not be enough in many cases.

During the study, it was noted that the obese mice did not move nearly as much as the leaner mice nor did they burrow like a normal mouse would. This lack of movement and burrowing activity is associated with depression and/or anxiety. Unfortunately, starting a new diet plan while not motivated and potentially in a depressed state of mind can create an atmosphere of doom, not one that is going to encourage a lot of weight loss success.


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