10 Ways For Successful In Vitro Fertilization (ivf)
Join 1000's of Authors at StreetArticles Today!

10 Ways for Successful In Vitro Fertilization (ivf)

Dr. Ioannis Toliopoulos, Ph.D., Molecular Biologist, Physiologist, Immunologist in Reproductive Medicine | Dr. Spyridon Papageorgiou, Gynecologist, Obstetrician, Specialized in infertility

The issue with the IVFs trials especially when they fail after many attempts are multidimensional. The anxiety of the couple to hold their baby in their arms has led sometimes to fast decisions, which result in IVF failure and a negative impact even on the couple’s health. That’s why this article is intended for couples that go under IVF trials and gives the ways that they have to know before they can try for an embryo transfer with higher chances to succeed in pregnancy. If the couple doesn’t follow the instructions below, the result will be to be prosecuted more and more and they will spend much money for many in vitro fertilization trials.

The 10 ways that the couple must follow are the following:

1) The exclusion that the husband’s sperm is responsible for infertility by testing sperm DNA fragmentation or DFI, which is very important because the usual sperm analysis is not enough to diagnose the genetic quality of the male’s genetic material. This means that DNA is fragmented into different sections because of smoking, alcohol, electromagnetism, oxidative stress, and other factors.

2) Checking the quality and quantity of women’s ovaries because if the quality of eggs is poor, then the result after a successful pregnancy would be RSA. One diagnostic marker is the hormone AMH (antimullerian hormone), which shows the fertility capability of women in terms of a number of ovaries. However, this marker is not adequate by itself to show that a woman has quality and quantity in ovaries.

3) Inhibin B is an additional test and is the hormone that shows us the quality of the ovaries. So, with these two tests, women know for sure whether they are fertile. This specific test is performed ONLY the 3rd day of the cycle.

4) The thickness of the endometrium must be examined carefully from the appropriate gynecologist and the women must be consulted in a suitable way, which is the higher thickness in order to have more chances for the embryo transfer to be successful. Statistically, the thicker the endometrium, the more chances for a successful pregnancy.

5) A very careful ultrasound from a specialized gynecologist who can see details in the anatomy of the woman’s reproductive system and can diagnose whether there is any anatomical problem so natural pregnancy can be achieved.

6) Immunological targeted testing including the number of Natural Killer Cells (NK cells) and the endometrial NK cells, which usually block pregnancy or the embryo transfer and is the MAIN cause for IVF failure most of the times.

7) The activity of NK cells blocks pregnancy because their receptors attack the embryo and lead it to apoptosis and don’t allow it to be implanted because they recognize it as an invader to the body. By this way, again IVF fails. This test is totally different from test number 6 and is very important for the stability of the pregnancy especially until the 3rd month of the gestation.

8) Embryotoxicity (ETA) is a very important test especially for women that fail in their IVF trials. It has been proposed that positive and negative embryotoxic factors provide the basis for a new classification of idiopathic recurrent pregnancy loss and in vitro fertilization (IVF) failure. The prevalence of embryotoxic activity among women experiencing recurrent pregnancy loss is 10% to 15% and among IVF failures is 20% to 25%. Embryotoxic factors have also been reported in women experiencing unexplained infertility and infertility associated with endometriosis.

9) The test platelet-leukocyte aggregates is a new test for identification of thrombotic events in RSAs and failed IVFs. Increased platelet-leucocyte aggregate has been reported in women that had RSAs or failed IVFs because of the thrombotic events that were diagnosed afterward. This test can help not only for diagnostic purposes but also to guide the physicians in order to perform the appropriate therapy with low molecular heparin for successful women’s pregnancy. This test can be performed in combination with the genetic thrombophilia panel testing. The methodology used for this test is flow cytometry and a green top tube is needed to run the test. The classical thrombophilia molecular tests are not enough to guide the woman for targeted and individualized therapy.

10) Blocking factors in a specific test for the couple, which clears whether there is histocompatibility in the couple’s immune system. This is only one test and does not require many tests as it was known up today and it was very costly. Blocking factors are not detected in most women with recurrent pregnancy losses (RPL) or unexplained imminent abortions (IA) or failed IVFs. The good news if a couple is positive in blocking factors is that there is a therapy that lasts one year and gives the chance the couple for successive pregnancy.

All the above ways increase the pregnancy success rates after IVF trials because these specific diagnostic tests and the targeted individualized therapies create higher chances for embryo transfer to be successful and the statistical analysis informs us for a rate over 80% of successful pregnancies.

However, it has to be clarified that the investigation, diagnosis, evaluation, and therapy MUST be performed by an expert and very well trained scientists in the field of reproductive medicine, so the couple can finally have their healthy baby with the lowest cost.

About the Authors:

Dr. Ioannis John Toliopoulos studied in Chicago, USA, molecular biology with full athletic and academic scholarship. Later, he studied the basic sciences in an English-Hungarian Medical University and then he returned to Greece where he was granted the Ph.D. diploma from Ioannina Medical University in the department of Physiology.Recently, he was trained by professors Dr. Roussev and Dr. Coulam in Chicago, where he was granted the Post Doc diploma in Reproductive and diagnostic immunology. At the end of 2006, he founded a nonprofit foundation called Konstantinion Research Center of Molecular Medicine and Biotechnology, where nowadays he is the president.

Dr. Spyros Papageorgiou graduated from Medical school in 1996. He specialized in gynecology-obstetrics and he was specially trained in embryo prenatal screening at LUBECK UKSH, Germany with certification from the Fetal Medical Foundation UK FMF-ID 97513.He is also trained under the guidance of Dr. Roumen Roussev in infertility, RSAs, and failed IVFs, and he keeps on getting educated in the new scientific data in reproductive medicine with main purpose the successful pregnancy of women that seek a baby.


Street Talk

No comments present
You May Also Like
Home Cleaning Products for Pregnancy
How safe are cleaning products for pregnant women? It is a known fact that there is a link between the exposure of cleaning products and respiratory problems. So imagine how that could affect an unborn baby in the mother's womb, even before inhaling his first breath. Prenatal exposure to home…
By: Afees Alli in  Health and Fitness  >  Womens Issues   Jun 08, 2016  
0
  Likes: 1

What Happens at Four Months Pregnant
A lady always feels frightened in a first pregnancy. It is the very solid time for a lady to born a baby. There are various stages of pregnancy. 4th month stage is always very risky & serious because, it has finished half time. It is the very imperative and vital…
By: Emma Mark in  Health and Fitness  >  Womens Issues   Jun 04, 2016  
0
  Likes: 1

5 Care After Abdominal Surgeries You Should Know
Women undergo abdominal surgeries for different reasons. The common types of surgeries include myomectomy, caesarean section ( C section )and Laparoscopy. Myomectomy is used for removing fibroids, Caesarean section is done for delivering babies surgically and Laparoscopy involves the treatment of endometriosis, pelvic inflammatory disease, ectopic pregnancy, ovarian cyst. All…
By: alihussan in  Health and Fitness  >  Womens Issues   Jun 01, 2016  
0
  Likes: 0

Renowned Asian Egg Donor Agency
The procedure of giving egg is acquainted with the point with help the infertile lady who can't get pregnant with her own particular eggs. Since its presentation, this Asian egg donation system is generally rehearsed universally and has turned into a to a great degree powerful medicinal methodology for both…
By: Andrew Simmons in  Health and Fitness  >  Womens Issues   May 31, 2016  
0
  Likes: 0

How to Ensure A Better Body Image After Baby
Body image is a huge concern for a majority of new moms. Some women are more than okay with their pregnant bodies. But there are many others who are shocked at, and sometimes in complete denial of, the changes their bodies may be going through. Pregnancy is a big deal…
By: davidjack2 in  Health and Fitness  >  Womens Issues   May 09, 2016  
0
  Likes: 0

Asian Egg Donors In US
For quite a long time, numerous couples who have been notable consider have depended upon Asian Egg Donors in US. All the more as of late, solid procedures for egg gathering and preparation have expanded richness alternatives for women whose own eggs are unviable. A few women give their eggs…
By: Andrew Simmons in  Health and Fitness  >  Womens Issues   Mar 29, 2016  
0
  Likes: 0

How to Treat the Hydrosalpinx And the Tubal Obstruction?
Although fallopian tube is the most important part of the female reproductive system and plays a vital role in the fertility process, it can also become the most vulnerable organ in your body. The frequent tubal obstruction and hydrosalpinx are also the common reason which leads to the clinic infertility.…
By: Issac Zhang in  Health and Fitness  >  Womens Issues   Mar 28, 2016  
0
  Likes: 0

Women's Health - A Women’s Day Special Initiative
Today’s women are headstrong, caring and visionaries. They wake up early, cook for family, pack tiffins, make their own to-do lists, manage work commitments, travel back home on time, cook-clean-care before calling it a day. She is not just an equal but actually works harder than others. She is considered…
By: Prakruti Jiyofresh in  Health and Fitness  >  Womens Issues   Mar 03, 2016  
0
  Likes: 2

Can You Have Sex With Endometriosis?
Endometriosis is the abnormal growth of cells similar to those that form the inside or lining the tissue of the uterus, but in a location outside of the uterus. Endometritis is usually not life-threatening, but it’s important to get it treated. During the treatment for endometriosis, there are many things…
By: sylvia0714 in  Health and Fitness  >  Womens Issues   Feb 25, 2016  
0
  Likes: 0

How Much Do You Know About Hydrotubation Technique?
Hydrotubation technique is the introduction of a fluid (usually a dye) through the cervix (neck) of the uterus under pressure to allow visualization, by laparoscopy, of the passage of the dye through the Fallopian tubes. Hydrotubation technique is to dilate or treat the fallopian tubes by an injection of a…
By: sylvia0714 in  Health and Fitness  >  Womens Issues   Feb 25, 2016  
0
  Likes: 1

Tubal Blockage With Hydrosalpinx is Often Cured By TCM Shortly
Mrs. Huang, 32 years old, is one of the individuals who got tubal blockage with hydrosalpinx. She had an ovarian dropsy in left fallopian tube and hydrops in proper tube. She could not get pregnant for two years. She took a laparoscopyin in the long run of 2007 to excise…
By: sylvia0714 in  Health and Fitness  >  Womens Issues   Feb 23, 2016  
0
  Likes: 0

Take - Home Chlamydia Tests Tied to Much More Screening
Women at danger for chlamydia infections are far more probably to acquire tested if they will do it at home as an alternative to going to a clinic, suggests new study. The study participants had all previously tested constructive for chlamydia and had been treated for the sexually-transmitted disease. But…
By: sylvia0714 in  Health and Fitness  >  Womens Issues   Feb 23, 2016  
0
  Likes: 0

What's the Connection Among PID And Abnormal Menstruation?
As is known, PID is really serious sexually transmitted diseases and may be classified into chronic endometriosis and chronic salpingitis.What's the connection between PID and abnormal menstruation? PID is usually a infection on female reproductive organs, so irreversible damages to the uterus, overies, fallopian tubes or other components from the…
By: sylvia0714 in  Health and Fitness  >  Womens Issues   Feb 22, 2016  
0
  Likes: 0

Can Herbal Medicine For Adenomyosis Be Far Better?
Adenomyosis has been not unfamiliar for women. Adenomyosis is actually a uncommon condition in which the cells of your endometrium grow in to the muscular walls of the uterus. Commonly, ladies might not have any outward symptoms this has occurred to them, but it may possibly turn into extremely painful.…
By: sylvia0714 in  Health and Fitness  >  Womens Issues   Feb 22, 2016  
0
  Likes: 0

Endometriosis Test - Deep Endometriosis is Usually Detected By MRI
A new study published within the on the internet edition of Radiology says that magnetic resonance imaging (MRI) may be made use of by radiologists to diagnose deep endometriosis and accurately locate lesions before surgery. "Pelvic MRI at three Tesla is a noninvasive approach that enables a complete examination with…
By: sylvia0714 in  Health and Fitness  >  Womens Issues   Feb 20, 2016  
0
  Likes: 0

Article Views: 946    Report this Article